Methyl 5-phenyl-1,2,4-oxadiazole-3-carboxylate - Names and Identifiers
Methyl 5-phenyl-1,2,4-oxadiazole-3-carboxylate - Physico-chemical Properties
Molecular Formula | C10H8N2O3
|
Molar Mass | 204.18 |
Melting Point | 113-116°C |
Storage Condition | Room Temprature |
Sensitive | IRRITANT |
MDL | MFCD00974530 |
Methyl 5-phenyl-1,2,4-oxadiazole-3-carboxylate - Risk and Safety
Methyl 5-phenyl-1,2,4-oxadiazole-3-carboxylate - Introduction
Methyl 5-phenyl-1,2,4-oxadiazole-3-carboxylate is an organic compound with the chemical formula C10H8N2O3. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless to light yellow crystal
-Melting point: 117-119°C
-Boiling point: 318.9°C
-Density: 1.30g/cm³
-Solubility: Soluble in organic solvents
Use:
- Methyl 5-phenyl-1,2,4-oxadiazole-3-carboxylate is an important organic synthesis intermediate. It can be used to synthesize a variety of compounds, such as drugs, pesticides and dyes in medicine.
Preparation Method:
- Methyl 5-phenyl-1,2,4-oxadiazole-3-carboxylate can be synthesized by the following steps:
1. The phenyl hydrazine reacts with nitrous acid to generate 5-phenyl -1,2,4-oxadiazole.
2. Under alkaline conditions, 5-phenyl-1,2,4-oxadiazole reacts with methyl formate to generate Methyl 5-phenyl-1,2,4-oxadiazole-3-carboxylate.
Safety Information:
- Methyl 5-phenyl-1,2,4-oxadiazole-3-carboxylate is generally relatively safe and harmless under normal use conditions.
-But it may cause irritation to the human body, so you should pay attention to avoid contact with skin and eyes during operation.
-Comply with safety procedures such as wearing protective gloves, goggles and lab coats when synthesizing and handling.
-If it is accidental contact or inhalation, immediately wash and appropriate first aid measures, and seek medical assistance when necessary.
Last Update:2024-04-09 20:49:11